PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL SENSITIVITY TEST OF THE AQUEOUS EXTRACT OF THE ROOT WOOD AND ROOT BARK OF Zanthozylum zanthozyloides (LAM.) ON CLINICAL ISOLATES

Zanthozylum zanthozyloides a common component of the rain forest vegetation is used as chewing stick. It known for its antioxidative, anti-inflammatory, antisickling, antibacterial, antiviral, antihepatoxicity, antiallegic, antitumor and antihypertensive properties. Phytochemicals present include Saponins, Tannins, Phenols, Cardiac glycoside, Flavonoids, Anthracene Alkaloids. The aqueous extracts root bark wood are bactericidal fungicidal against selected clinical microorganisms such Staphylococcus epidermidis, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Aspergillus niger, Candida albicans Rhizopus oryzae. Of all tested mirabilis was most sensitive to extract Z. at concentration 100mg/ml (18.00 mm), while least microorganism K. pneumoniae 12.5mg/ml (1.67 mm). S. epidermidis showed highest sensitivity 19.67 mm (100mg/ml) E. coli 1.67 25mg/ml. Majority antimicrobial drugs in this study were less effective bacteria fungi isolates compared plant extracts, indicating relevance treatment infectious diseases. Though possesses more bioactive materials, result provides basis development new pharmaceutical from both wood, or whole